Programme

Precision Oncology • Molecular Tumour Board • Modern Radiotherapy • Clinical Grand Round

Time SCIENTIFIC PROGRAMME
12:30–14:00
Registration & Welcome Coffee
14:00 -14:30
Opening Ceremony — Welcome addresses by MARO, institutional and international representatives
14:30 -15:00
Opening Plenary: Multidisciplinary Precision Oncology — Translating Evidence into Better Clinical Outcomes
15:00 – 16:30
SESSION 1 • PRECISION ONCOLOGY IN DAILY CLINICAL PRACTICE

Session chairs: Pathologist • Molecular biologist • Medical oncologist • Radiation oncologist (TBC)
15:00 – 15:20
The modern diagnostic pathway: integrating morphology, immunohistochemistry, imaging and molecular classification
15:20 – 15:40
Choosing the right biomarker test: tissue, NGS and circulating tumour DNA in clinical practice
15:40 – 16:00
From molecular alteration to treatment: evidence levels, ESCAT actionability and clinical prioritisation
16:00 – 16:30
Live Molecular Tumour Board: standard of care, clinical trial or off-label treatment?
16:30 – 17:00
Coffee Break & Poster Viewing
17:00 – 18:30
SESSION 2 • MODERN RADIOTHERAPY: PRECISION, INTEGRATION AND CLINICAL IMPACT

Session chairs: Radiation oncologist • Medical physicist • Medical oncologist • Radiologist (TBC)
17:00 – 17:20
Precision radiotherapy today: IGRT, VMAT, motion management and online adaptive treatment
17:20 – 17:40
SRS and SBRT across the disease course: early-stage, oligometastatic and oligoprogressive cancer
17:40 – 18:00
Combining radiotherapy with immunotherapy and targeted agents: efficacy, sequencing and safety
18:00 – 18:30
Radiotherapy clinical case board: target definition, dose, fractionation and toxicity trade-offs
18:30 – 19:15
MULTIDISCIPLINARY CLINICAL GRAND ROUND • THE LOCALLY ADVANCED PATIENT

Panel: Surgeon • Pathologist • Radiologist • Medical oncologist • Radiation oncologist (TBC)
18:30 – 19:15
One complex case, five perspectives: diagnosis, resectability, systemic therapy, radiotherapy and treatment sequencing
19:30
Welcome reception

Clinical MDT Tracks • Breast • Lung • Melanoma & Skin Cancers • Neuro-Oncology

Time SCIENTIFIC PROGRAMME
08:30–10:30
SESSION 3 • BREAST CANCER: FROM MOLECULAR SUBTYPE TO AN INTEGRATED TREATMENT PLAN

Session chairs: Breast surgeon • Pathologist • Radiologist • Medical oncologist • Radiation oncologist (TBC)
08:30 -08:50
Clinical work-up and risk stratification: imaging, pathology, biomarkers and genomic signatures
08:50 – 09:10
Neoadjuvant and post-neoadjuvant strategies in HER2-positive and triple-negative breast cancer
09:10 – 09:30
HR-positive/HER2-negative disease: precision escalation and de-escalation in early and advanced settings
09:30 – 09:50
Modern breast radiotherapy: partial-breast treatment, hypofractionation, boost and regional nodal irradiation
09:50 – 10:10
Surgical decision-making after systemic therapy: breast and axillary management
10:10- 10:30
Breast MDT case: balancing local control, systemic risk and patient preference
10:30 – 11:00
Coffee Break & Poster Viewing
11:00 – 13:00
SESSION 4 • LUNG CANCER: STAGE-ADAPTED MULTIDISCIPLINARY AND PRECISION TREATMENT

Session chairs: Radiation oncologist • Medical physicist • Medical oncologist • Radiologist (TBC)
11:00 – 11:20
From nodule to molecular profile: optimal tissue acquisition, staging and biomarker testing
11:20 – 11:40
Early-stage NSCLC: surgery, sublobar resection or stereotactic body radiotherapy?
11:40 – 12:00
Resectable NSCLC: perioperative immunotherapy and targeted therapy in multidisciplinary practice
12:00 – 12:20
Unresectable stage III NSCLC: modern chemoradiotherapy, planning quality and consolidation
12:20 – 12:40
Metastatic NSCLC: precision systemic therapy and local treatment for oligometastatic/oligoprogressive disease
12:40 – 13:00
Thoracic MDT case: staging uncertainty, operability and sequencing of systemic and local therapy
13:00 – 14:00
Lunch & Poster Viewing
14:00 – 15:40
SESSION 5 • MELANOMA AND SKIN CANCERS: FROM CURATIVE SURGERY TO COMPLEX SYSTEMIC CARE

Session chairs: Dermatologist • Pathologist • Surgeon • Medical oncologist • Radiation oncologist (TBC))
14:00 – 14:20
Pathology and imaging for clinical decisions: staging, margins, nodal assessment and predictive biomarkers
14:20 – 14:40
Neoadjuvant and adjuvant therapy in high-risk melanoma
14:40 – 15:00
Advanced melanoma: sequencing immunotherapy and targeted therapy
15:00 – 15:20
Radiotherapy in melanoma and complex skin cancer: adjuvant treatment, palliation and stereotactic approaches
15:20 – 15:40
Skin cancer MDT case: organ preservation, local control and systemic options
15:40 – 16:10
Coffee Break
16:10 – 17:50
SESSION 6• NEURO-ONCOLOGY: INTEGRATED CARE FOR PRIMARY AND METASTATIC BRAIN TUMOURS

Session chairs: Session chairs: Neurosurgeon • Neuropathologist • Neuroradiologist • Medical oncologist • Radiation oncologist (TBC)
16:10 – 16:30
Integrated neuropathological diagnosis: translating WHO molecular classification into practice
16:30 – 16:50
Newly diagnosed and recurrent diffuse gliomas: molecularly informed systemic treatment
16:50 – 17:10
Modern radiotherapy for CNS tumours: target definition, precision planning, re-irradiation and toxicity reduction
17:10 – 17:30
Brain metastases: surgery, SRS/SRT and systemic therapy in a rapidly changing landscape
17:30 – 17:50
Neuro-oncology MDT case: integrating imaging, pathology, function and prognosis
17:50 – 18:30
Young Investigators’ Forum & Moderated Poster Walk
20:00
Congress DInner

Clinical MDT Tracks • Gynaecological • Colorectal • Gastric & Upper GI Cancers

Time SCIENTIFIC PROGRAMME
08:30–10:30
SESSION 7 • GYNAECOLOGICAL CANCERS: PATHOLOGY-DRIVEN, MULTIMODAL, PERSONALISED

Session chairs: Gynaecologic oncologist • Pathologist • Medical oncologist • Radiation oncologist (TBC)
08:30 -08:50
Molecular classification in endometrial and ovarian cancer: practical pathology for treatment planning
08:50 – 09:10
Locally advanced cervical cancer: imaging, concurrent systemic therapy, precision EBRT and image- guided brachytherapy
09:10 – 09:30
Endometrial cancer: risk-adapted adjuvant treatment and systemic options in advanced disease
09:30 – 09:50
Ovarian cancer: surgery, maintenance strategies and biomarker-guided treatment
09:50 – 10:10
Recurrent gynaecological cancers: immunotherapy, targeted treatment, salvage surgery and re-irradiation
10:10- 10:30
Gynaecological MDT case: integrating pathology, operability, radiotherapy and systemic therapy
10:30 – 11:00
Coffee Break & Poster Viewing
11:00 – 12:40
SESSION 8 • COLORECTAL CANCER: ORGAN PRESERVATION, PRECISION AND OLIGOMETASTATIC CARE

Session chairs: Colorectal surgeon • Gastroenterologist • Pathologist • Medical oncologist • Radiation oncologist (TBC))
11:00 – 11:20
Rectal cancer after total neoadjuvant therapy: selection, sequencing and response assessment
11:20 – 11:40
Watch-and-wait and organ preservation: evidence, surveillance and shared decision-making
11:40 – 12:00
Molecularly defined metastatic colorectal cancer: treatment pathways and resistance
12:00 – 12:20
Liver-limited and oligometastatic disease: surgery, ablation and stereotactic radiotherapy
12:20 – 12:40
Colorectal MDT case: sequencing local and systemic treatment across disciplines
12:40 – 13:40
Lunch & Poster Viewing
13:40 – 15:20
SESSION 9 • GASTRIC AND UPPER GI CANCERS: BIOMARKERS AND MULTIMODAL STRATEGIES

Session chairs: Upper GI surgeon • Gastroenterologist • Pathologist • Medical oncologist • Radiation oncologist (TBC)
13:40 – 14:00
Essential pathology and biomarkers in gastric/GEJ cancer: HER2, PD-L1, MSI/MMR and CLDN18.2
14:00 – 14:20
Perioperative therapy for resectable gastric and gastro-oesophageal junction cancer
14:20 – 14:40
Advanced gastric cancer: biomarker-directed first-line and later-line strategies
14:40 – 15:00
Oesophageal and GEJ cancer: definitive chemoradiotherapy, neoadjuvant therapy and surgical selection
15:00 – 15:20
Upper GI MDT case: from endoscopy and pathology to a coordinated treatment plan
15:20 – 15:50
Coffee Break
15:50 – 16:50
FINAL MULTIDISCIPLINARY CLINICAL GRAND ROUND • THREE DIFFICULT CASES

Panel: Pathologist • Radiologist • Surgeon • Medical oncologist • Radiation oncologist (TBC)
15:50 – 16:50
Case-based decisions in precision oncology: interpreting biomarkers, defining treatment intent and sequencing surgery, systemic therapy and radiotherapy
16:50 – 17:20
Awards, Congress Conclusions & Closing Ceremony